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R Wagener Selected Research

Matrilin Proteins

1/2021The Matrilin-3 T298M mutation predisposes for post-traumatic osteoarthritis in a knock-in mouse model.
10/2005Matrilin-3 mutations that cause chondrodysplasias interfere with protein trafficking while a mutation associated with hand osteoarthritis does not.
4/2002Matrilin-3 in human articular cartilage: increased expression in osteoarthritis.
2/2000Molecular structure and tissue distribution of matrilin-3, a filament-forming extracellular matrix protein expressed during skeletal development.

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R Wagener Research Topics

Disease

3Osteoarthritis
01/2021 - 04/2002
1type 2 alpha 1 Collagenopathy
01/2021
1Osteogenesis Imperfecta (Lobstein Disease)
01/2020
1Infectious Arthritis (Septic Arthritis)
10/2019
1Cicatrix (Scar)
10/2016
1Scleroatonic muscular dystrophy
09/2014
1Muscular Dystrophies (Muscular Dystrophy)
09/2014
1Fibrosis (Cirrhosis)
09/2014
1Bethlem myopathy
09/2014
1Muscular Diseases (Myopathy)
09/2014
1Pseudoachondroplasia
10/2005
1Osteochondrodysplasias (Spondyloepiphyseal Dysplasia)
10/2005
1Chondrosarcoma
02/2000

Drug/Important Bio-Agent (IBA)

4Matrilin ProteinsIBA
01/2021 - 02/2000
3CollagenIBA
01/2020 - 02/2000
2Proteins (Proteins, Gene)FDA Link
01/2020 - 10/2005
12-oxoglutarate 3-dioxygenase prolineIBA
01/2020
1cis-trans-IsomerasesIBA
01/2020
1Collagen Type I (Type I Collagen)IBA
01/2020
1C-Type Lectins (C-Type Lectin)IBA
10/2019
1Antimicrobial PeptidesIBA
10/2019
1Peptides (Polypeptides)IBA
10/2019
1Biomarkers (Surrogate Marker)IBA
10/2016
1PolymersIBA
09/2014
1Fibrillar CollagensIBA
09/2014
1Cartilage Oligomeric Matrix ProteinIBA
10/2005
1Extracellular Matrix ProteinsIBA
04/2002